Influenza H1N1 neurology

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Influenza H1N1 neurology. Seizures: this is the commonest presentation, Guillain Barre syndrome (GBS). Fully referenced neurology checklist.

Neurological presentations

  • Seizures: this is the commonest presentation
  • Guillain Barre syndrome (GBS)
  • Encephalopathy: this may be acute necrotizing
  • Acute demyelinating encephalomyelopathy (ADEM)
  • Stroke
  • Transverse myelitis (TM)
  • Paroxysmal kinesigenic dyskinesia (PKD)
  • Malignant cerebral oedema
  • Distal forearm myositis

Pathogenesis

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Magnetic resonance imaging (MRI): features

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Treatment

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References

  1. Cardenas G, Soto-Hernandez JL, Diaz-Alba A, et al. Neurological events related to influenza A (H1N1) pdm09. Influenza Other Respir Viruses 2014; 8:339-346.
  2. Khandaker G, Zurynski Y, Buttery J, et al. Neurologic complications of influenza A (H1N1) pdm09. Surveillance in 6 paediatric hospitals. Neurology 2012; 79:474-481.
  3. Spalice A, Del Balzo F, Nicita F, et al. Teaching Neuroimages: Acute necrotizing encephalopathy during novel influenza A (H1N1) virus infection. Neurology 2011; 77:e121.
  4. Hur YJ, Huang T. Secondary paroxysmal dyskinesia associated with 2009 H1N1 infection. Korean J Pediatr 2013; 56:42-44.
  5. Kahle KT, Walcott BP, Nahed BV, et al. Cerebral edema and a transtentorial brain hermniation syndrome associated with pandemic swine flu influenza A (H1N1) virus infection. J Clinical Neurosci 2011; 18:1245-1248.
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