Radiation necrosis v tumour recurrence

Evidence-based neurology checklist on radiation necrosis v tumour recurrence: Features common to radiation necrosis and tumour recurrence Enhancement Oedema Mass effect Necrosis Cavitation Hypermetabolism: on positron emission tomography (PET) scans Features of tumour recurrence Features of…

Features common to radiation necrosis and tumour recurrence

  • Enhancement
  • Oedema
  • Mass effect
  • Necrosis
  • Cavitation
  • Hypermetabolism: on positron emission tomography (PET) scans

Features of tumour recurrence

Features of radiation necrosis

References

  1. Ricci PE, Karis JP, Heisetman JE, Fram EK, Bice AN, Drayer BP. Differentiating recurrent tumour from radiation necrosis: time for re-evaluation of positron emission tomography? Am J Neuroradiol 1998; 19:407-413.
  2. Mullins ME, Barest GD, Schaefer PW, Hochberg FH, Gonzalez RG, Lev MH. Radiation necrosis versus glioma recurrence: conventional MR imaging clues to diagnosis. Am J Neuroradiol 2005; 26:1967-1972.
  3. Weybright P, Sundgren PC, Maly P, et al. Differentiation between brain tumour recurrence and radiation injury using MR spectroscopy. Am J Roentgenol 2005; 185:1471-1476.
  4. Grossman RI, Yousem DM. The requisites Neuroradiology. 2nd edition. Mosby Philadelphia 2003 p169.
  5. Zakhari N, Taccone MS, Torres C, et al. Diagnostic accuracy of centrally restricted diffusion in the differentiation of treatment-related necrosis from tumor recurrence in high-grade gliomas. Am J Neuroradiol 2018; 39:260-264. 
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